Simon Schwab

Simon Schwab, Dr.

Postdoctoral Fellow

Phone: 44976

Short Biography

I joined the Center for Reproducible Science (CRS) at the EBPI as a postdoctoral fellow with Leo Held. Before working at UZH, I was an SNF mobility fellow at Warwick University (Department of Statistics) and Oxford University (Big Data Institute) to develop methods for functional brain connectivity. I completed a master’s degree in psychology (major) and computer science (minor) as well as a PhD in Neuroscience at the University of Bern. My main expertise is methods in psychiatry research, for example, analysis of neuroimaging data and the development of novel methods in computational neuroscience to study brain connectivity.

Main Responsibilities

My main responsibilities are teaching courses in Good Research Practice across faculties. I organize a journal club related to reproducible research named ReproducibiliTea, and I teach biostatistics at medical school. I'm currently writing a series named Reproducibility Notes in the journal Significance.

Research Projects

My current research projects and preregistered study protocols are listed below.

  1.  Assessing publication bias in clinical trials across different specialties in medicine
  2. Investigating the appropriate use of ANCOVA in medicine, neuroscience and psychology


  • Audrey Yeo (StwF funding 2019-2000)
  • Giuachin Kreiliger (Master Thesis in Biostatistics, 2019)

Current Funding

I receive funding from StwF for my project "Computational infrastructure to foster open and reproducible reanalysis of scientific data (FORRESD). The address of the server is and is used in the above-mentioned research projects to build large scale databases for meta-research and for the reanalysis of published research.

Recent Publications (peer-reviewed)

  1. Gysin-Maillart, A., Soravia, L., & Schwab, S. (2020). Attempted suicide short intervention program influences coping among patients with a history of attempted suicide. Journal of Affective Disorders, 264, 393–399. doi:10.1016/j.jad.2019.11.059 
  2. Held, L., & Schwab, S. (2020). Improving the reproducibility of science. Significance, 17(1), 10–11. doi:10.1111/j.1740-9713.2020.01351.x
  3. Lund, M. J., Alnæs, D., Schwab, S., van der Meer, D., Andreassen, O. A., Westlye, L. T., & Kaufmann, T. (in press). Differences in directed functional brain connectivity related to age and sex. Human Brain Mapping. doi:0.1002/hbm.25116
  4. Schwab, S., Afyouni, S., Chen, Y., Han, Z., Guo, Q., Dierks, T., Wahlund, L.-O., & Grieder, M. (in press). Functional connectivity alterations of the temporal lobe and hippocampus in semantic dementia and Alzheimer’s disease. Journal of Alzheimer's Diseasedoi:10.1101/322131
  5. Schwab, S., Federspiel, A., Morishima, Y., Nakataki, M., Strik, W., Wiest, R., Heinrichs, M., de Quervain, D., & Soravia, L. M. (2020). Glucocorticoids and cortical decoding in the phobic brain. Psychiatry Research: Neuroimaging, 300, 111066. doi:10.1016/j.pscychresns.2020.111066
  6. Schwab, S., & Held, L. (2020). Science in the face of Covid-19: faster, better, stronger? Retrieved May 12, 2020, from
  7. Schwab, S., & Held, L. (2020). Different worlds: confirmatory versus exploratory research. Significance, 17(2), 8–9. doi:10.1111/1740-9713.01369

See Simon Schwab in PubMed for more publications.