Research

Publications

Find our publications on the Zurich Open Repository and Archive (ZORA).

Research Projects

CRS develops novel methodology related to reproducibility and replicability, and contributes to the improvement the quality of scientific investigation using meta-science.

See below for a summary of our research projects.

Design and Analysis of Replication Studies

Leonhard Held, Charlotte Micheloud, Samuel Pawel
SNF Project: Reverse-Bayes Design and Analysis of Replication Studies
Royal Statistical Society Read paper: A New Standard for the Analysis and Design of Replication Studies
Key note talk at the RSS meeting in September 2019
Paper on arXiv: Sample Size Calculation for Replication Studies
Paper on PLOS One: Predictive Evaluation of Replication Studies

Assessing treatment effects and publication bias across different specialties in medicine: a large empirical study of the Cochrane Database of Systematic Reviews

Simon Schwab, Giuachin Kreiliger, Leonhard Held
Registered study protocol and preprint are available. The project received funding from the StwF (STWF-19-007).

Investigating the appropriate use of ANCOVA in medicine, neuroscience and psychology

Simon Schwab, Audrey Yeo
This project seeks to assess the use of analysis of covariance (ANCOVA) in various scientific fields. The work considers publications from the fields neuroscience, medicine, and psychology, as well as certain interdisciplinary subjects. Reanalysis of the original work was done to determine whether ANCOVA has been utilised appropriately. See the OSF repository of the project.

Biostatisticians’ Impact on Quality in Medical Research (BIQMR)

Eva Furrer, Michael Hediger, Ulrike Held, Klaus Steigmiller
Presentation of the protocol at the Conference of the Austro-Swiss Region of the International Biometric Society in September 2019: A meta-research study on quality and impact of biostatisticians in health research
Registered Report at Plos One: Is reporting quality in medical publications associated with biostatisticians as co-authors? A registered report protocol

Reseach Infrastructure

Forresd - Foster Open and Reproducible Reanalysis of Scientific Data
Simon Schwab, Eva Furrer, Leonhard Held
We gratefully receive funding by the StwF for this project (STWF-19-007).
Forresd is a Linux analysis server for the CRS staff, CRS members and CRS fellows.
The address is crs.ebpi.uzh.ch and can be accessed via SSH or x2go.
Access from home is possible using VPN.
More information and request account here (PDF, 449 KB).

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