Find our publications on the Zurich Open Repository and Archive (ZORA).

Research Projects

CRS develops novel methodology related to reproducibility and replicability, and contributes to the improvement the quality of scientific investigation using meta-science.

See below for a summary of our research projects.



Design and Analysis of Replication Studies

Image Design and Analysis of Replication Analysis


Assessing treatment effects and publication bias across different specialties in medicine: a large empirical study of the Cochrane Database of Systematic Reviews

Image Assessing Treatment Effects


Investigating the appropriate use of ANCOVA in medicine, neuroscience and psychology

  • Simon Schwab, Audrey Yeo
  • This project seeks to assess the use of analysis of covariance (ANCOVA) in various scientific fields. The work considers publications from the fields neuroscience, medicine, and psychology, as well as certain interdisciplinary subjects. Reanalysis of the original work was done to determine whether ANCOVA has been utilised appropriately. See the OSF repository of the project.



Biostatisticians’ Impact on Quality in Medical Research (BIQMR)


Reseach Infrastructure

  • Forresd - Foster Open and Reproducible Reanalysis of Scientific Data 
    Simon Schwab, Eva Furrer, Leonhard Held
    We gratefully receive funding by the StwF for this project (STWF-19-007).
    Forresd is a Linux analysis server for the CRS staff, CRS members and CRS fellows.
    The address is and can be accessed via SSH or x2go.
    Access from home is possible using VPN.
    More information and request account here (PDF, 449 KB).